Description
Cyclic synthetic analogue of α-MSH with broader receptor binding than MT-1: activates MC1R, MC3R, MC4R, and MC5R. Significantly more potent than MT-1 and produces stronger tanning and sexual effects. Led to development of PT-141 (bremelanotide) as a sexual dysfunction treatment.
Benefits:
Potent skin tanning (even with minimal UV exposure); strong sexual arousal / libido enhancement; potential appetite suppression and fat loss (MC4R); led directly to development of PT-141
Side Effects:
Significant nausea (most commonly reported); vomiting; prolonged spontaneous erections (priapism risk); facial flushing; fatigue; yawning and stretching behavior; darkening of moles (potential melanoma risk); hyperpigmentation; increased blood pressure
For laboratory research only — not for human consumption.





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