Description
A cosmetic peptide (palmitoyl-pentapeptide) developed by Sederma that signals skin fibroblasts to increase collagen I, III, IV, fibronectin, and hyaluronic acid production. Matrixyl 3000 is a blend of Matrixyl with palmitoyl tetrapeptide-7. One of the best-studied cosmetic ingredients available.
Benefits:
Collagen synthesis stimulation (up to 85-89% increase in vitro); clinically demonstrated wrinkle depth reduction (~25% in 12-week RCT); improved skin firmness and elasticity; skin hydration; suitable for sensitive skin; no photosensitivity (unlike retinoids); can combine with most actives
Side Effects:
Mild skin irritation (1-3%); allergic contact dermatitis (<1%); temporary sensitivity (<2%); no serious side effects documented; no photosensitivity
For laboratory research only — not for human consumption.




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