Description
Semaglutide is a synthetic 31-residue analogue of glucagon-like peptide-1 (7–37). Numbered from that parent sequence, it has α-aminoisobutyric acid (Aib) at position 8, Arg at position 34, and an octadecanedioic (C18) fatty diacid attached to the Lys26 side chain through a γ-glutamyl–bis(AEEA) linker.
Specifications
- Sequence: H-Aib-EGTFTSDVSSYLEGQAA-K(AEEA-AEEA-γGlu-CO-(CH2)16-CO2H)-EFIAWLVRGRG-OH (Aib = α-aminoisobutyric acid; AEEA = 8-amino-3,6-dioxaoctanoic acid)
- Molecular formula: C187H291N45O59
- Molecular weight: 4113.58 g/mol
- CAS: 910463-68-2
- Purity: 99.8% (HPLC)
- Form: 30 mg lyophilized powder, sealed vial
- Storage: −20 °C, lyophilized; 24 months
Quality documentation
A lot-specific certificate of analysis (COA) is available on request.




